Everyone, at some point in their life, have experienced getting sick from another human being. Whether it was contracting chicken pox playing kickball in elementary school or kissing a significant other, it is not uncommon to contract an infectious disease from another person.
A disease is defined as an abnormal condition of an organism that impairs bodily functions, usually indicated by specific symptoms and signs. Infectious diseases, in particular, are caused by external factors such as viruses, bacteria, and other harmful pathogens. It may be as simple as the coughing of co-worker or carelessness in the hospital that can cause you to contract an infectious disease. These diseases range from the common cold to deadly sexually transmitted diseases.
Infectious diseases may seem like an omnipresent part of human life, but there are definitely steps that you can take to avoid contracting such infectious diseases. Being careful and conscious of your safety, along with knowing your surrounding environment can help you avoid contract an infectious disease. Your skin is the main defensive mechanism against infectious diseases, but some diseases will find other ways to enter your body.
The rest of this article will give you tips on how to avoid contracting infectious diseases. Follow these tips to change your behavior and avoid the spread and contraction of these diseases. Read more »
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Posted in medicalmatrix | February 13, 2010 | 
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Infectious disease is disease caused by a pathogen which enters the body and triggers the development of an infection. Infectious diseases have a range of causes, and they can be found all over the world. These diseases are considered contagious or communicable, meaning that they can be passed from person to person. It is also possible for such diseases to spread indirectly through unhygienic conditions, or from animals to people, in which case they are known as zoonotic diseases.
A variety of pathogens can be responsible for infectious disease, including viruses, bacteria, fungi, protozoans, and prions. Within these large categories of infectious organisms, there are numerous modes of transmission and a colorful assortment of symptoms, although surprisingly few organisms cause infectious disease, when one considers the diversity of viral, bacterial, fungal, and protozoan life. In order to treat an infectious disease, doctors must be able to knock out the source of the infection and repair the damage it has done to the body. Many infectious diseases make the body vulnerable to secondary infections, in which other organisms move in to take advantage of a weakened immune system, and this can be very problematic.
The study of infectious disease is known as epidemiology. Epidemiologists work to determine the source of an infectious disease so that they can develop new treatment approaches. They also identify emerging outbreaks, which may develop into epidemics or pandemics, and areas where a disease is endemic, meaning that it occurs regularly. Malaria, for example, is endemic to some regions of Africa and Southeast Asia. Read more »
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Background
Anemia, like a fever, is a symptom of disease that requires investigation to determine the underlying etiology. Often, practicing physicians overlook mild anemia. This is similar to failing to seek the etiology of a fever. The purpose of this article is to provide a method of determining the etiology of an anemia.
Anemia is strictly defined as a decrease in red blood cell (RBC) mass. Methods for measuring RBC mass are time consuming, are expensive, and usually require transfusion of radiolabeled erythrocytes. Thus, in practice, anemia is usually discovered and quantified by measurement of the RBC count, hemoglobin (Hb) concentration, and hematocrit (Hct). These values should be interpreted cautiously because they are concentrations affected by changes in plasma volume. For example, dehydration elevates these values, and increased plasma volume in pregnancy can diminish them without affecting the RBC mass.
Pathophysiology
Erythroid precursors develop in bone marrow at rates usually determined by the requirement for sufficient circulating Hb to oxygenate tissues adequately. Erythroid precursors differentiate sequentially from stem cells to progenitor cells to erythroblasts to normoblasts in a process requiring growth factors and cytokines. This process of differentiation requires several days. Normally, erythroid precursors are released into circulation as reticulocytes.
Reticulocytes remain in the circulation for approximately 1 day before reticulin is excised by reticuloendothelial cells with the delivery of the mature erythrocyte into circulation. The mature erythrocyte remains in circulation for about 120 days before being engulfed and destroyed by phagocytic cells of the reticuloendothelial system. Read more »
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Background
Malaria, which predominantly occurs in tropical areas, is a potentially life-threatening disease caused by infection with Plasmodium protozoa transmitted by an infective female Anopheles mosquito vector. Individuals with malaria may present with fever and a wide range of symptoms.
The 4 Plasmodium species known to cause malaria include Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. A fifth species, Plasmodium knowlesi, has recently been identified as a clinically significant pathogen in humans. Timely identification of the infecting species is extremely important, as P falciparum infection can be fatal and is often resistant to standard chloroquine treatment. In some cases, individuals with malaria are infected with multiple Plasmodium species. P falciparum and P vivax are responsible for most new infections. Each Plasmodium species has a defined area of endemicity, although geographic overlap is common. Species can usually be distinguished by morphology on a blood smear. P falciparum is distinguished from the rest of plasmodia by its high level of parasitemia and the banana shape of its gametocytes.
Malaria in travelers typically manifests weeks after the individual leaves the endemic area. Presentation more than 4 weeks after returning from the endemic area is unusual. In some individuals, disease manifests months or years later, usually due to the presence of P vivax or P ovale hypnozoites, which can remain dormant in the liver and reactivate years after infection. Relapse with P vivax or P ovale infection is rare more than 5 years after initial infection. Because symptomatic delay is common, history of even a remote exposure to an endemic area should be elicited. Symptoms of malaria are nonspecific, and, because timely diagnosis and treatment are necessary, malaria should be considered in all patients from tropical areas who present with fever. Read more »
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This article focuses on common bacterial infections in pregnancy and describes the manifestations of these infections and the therapies used to treat them.
Bacterial infections can affect pregnant women from implantation of the fertilized ovum through the time of delivery and peripartum period. They may also affect the fetus and newborn. Many women with these infections are asymptomatic, necessitating both a high degree of clinical awareness and adequate screening.
Grop B Streptococcus
Group B Streptococcus (GBS) is the most common cause of life-threatening infections in newborns; thus, GBS is the primary focus of any discussion about infections and pregnancy. Infections caused by GBS affect both mother and child. Since the emergence of this pathogen in the 1970s, the increased use of intrapartum prophylaxis has decreased the infection rate by 70%.
Etiology
Streptococcus agalactiae, or GBS, is a facultative, beta-hemolytic, fastidious, gram-positive coccus. GBS can be found as part of normal vaginal, rectal, and oral flora. The virulence of the organism depends largely on the polysaccharide capsule.
Transmission
Twenty to 25% of pregnant women are asymptomatic carriers of vaginal or rectal GBS. Intrapartum transmission occurs via ascending spread or at the time of delivery.
Clinical spectrum
Because only 0.5-1% of mothers who carry GBS develop signs and symptoms of disease, clinical diagnosis of GBS infection can be problematic.
In pregnant women, GBS is a cause of cystitis, amnionitis, endometritis, and stillbirth. Occasionally, GBS has caused endocarditis and meningitis in pregnant women, while, in postpartum women, GBS has been identified as a cause of urinary tract infections (UTIs) and pelvic abscesses. Read more »
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